Nitroglycerin (Sublingual) Detailed Information

The active ingredient in this medication is **Nitroglycerin**. This compound acts as a potent vasodilator, which means it relaxes and expands blood vessels, reducing the workload on the heart and improving oxygen supply to cardiac muscles. Other inactive ingredients may include lactose, starch, and microcrystalline cellulose, depending on the formulation.

As with any medication, Nitroglycerin can cause side effects, ranging from mild to severe. Common side effects include:

• Headache (very common and usually temporary as the body adjusts)
• Dizziness or lightheadedness, especially when standing up suddenly
• Low blood pressure (hypotension), leading to fainting in some cases
• Flushing of the skin or warmth sensation
• Nausea or vomiting

Less common but more serious side effects include:

• Severe hypotension, which may require medical intervention
• Blurred vision or confusion
• Allergic reactions such as rashes, swelling of the face or throat, and difficulty breathing

If you experience severe dizziness, fainting, or prolonged chest pain despite taking Nitroglycerin, seek medical help immediately.

Nitroglycerin sublingual tablets are designed to be taken as needed at the first sign of chest pain. The tablet should be placed under the tongue and allowed to dissolve naturally—do not swallow or chew it. If chest pain persists after 5 minutes, a second dose may be taken. A maximum of three doses can be taken within a 15-minute period.

For prevention, doctors may prescribe scheduled doses before activities known to trigger angina, such as exercise or stress-inducing situations.

Nitroglycerin can interact with certain medications, leading to potential complications. Consult your doctor before combining it with:

• Erectile dysfunction drugs (Sildenafil, Tadalafil, Vardenafil): These can cause dangerous drops in blood pressure.
• Blood pressure medications: Some antihypertensives may enhance Nitroglycerin’s effects, leading to excessive hypotension.
• Alcohol: Consumption while taking Nitroglycerin may increase the risk of severe dizziness or fainting.
• Other nitrate medications: Using multiple nitrate-based drugs can increase the likelihood of severe hypotension.

Always inform your healthcare provider about all medications and supplements you are taking.

Nitroglycerin sublingual tablets typically begin working within **1-5 minutes** after placement under the tongue. The effects usually last around **30 minutes**. If symptoms do not improve within the first dose, subsequent doses should be administered at 5-minute intervals as needed.

For sustained angina prevention, extended-release Nitroglycerin formulations may be prescribed.

If you experience any of the following severe side effects, seek emergency medical attention immediately:

• Severe dizziness or fainting
• Persistent or worsening chest pain
• Irregular or rapid heartbeat
• Severe allergic reactions, including swelling of the lips, tongue, or throat

Do not operate heavy machinery or drive after taking Nitroglycerin, as it may cause sudden dizziness.